TP53 Intronic Mutations in Bovine Enzootic Hematuria–Associated Urinary Bladder Tumors

Bovine papillomavirus type 2 detection in the urinary bladder of cattle with chronic enzootic haematuria.

The bovine papillomavirus type 2 (BPV-2) involvement in the aetiology of chronic enzootic haematuria associated to bracken fern ingestion has been suggested for a long time. However, a few reports have shown the presence of the BPV-2 in urinary bladder tumors of cattle. The aim of this study was to investigate the presence of the BPV-2 infection in the urinary bladder of cattle with chronic enz...

Papilloma-like virus from bovine urinary bladder tumors.

TP53 gene mutations as an independent marker for urinary bladder cancer progression.

This study evaluates the influence of the TP53 genetic status on tumour recurrence and progression with a highly effective electrophoretic technique. DNA from tissue of 75 non-invasive urinary bladder cancers was PCR amplified in the TP53 exons 5-8 and run on horizontal polyacrylamide gels under defined temperature conditions to yield specific gel shifts. Kaplan-Meier and Cox-Regression analysi...

Enzootic Bovine Leukosis

Both EBL and SBL occur in southern Africa and in the Southern African context it will therefore be very important to accurately differentiate between EBL and SBL. The epidemiology, direct and indirect economic impact, diagnosis and most importantly control and eradication of EBL is markedly different to that of SBL. Globally EBL infection may also place severe restrictions on the import and exp...

Enzootic Bovine Leukosis

Bovine Leukemia Virus (BLV) is the etiologic agent of Enzootic Bovine Leukosis, a retrovirus exogenous to the bovine species. Once infected, there is no detectable viraemia but instead there is a strong and persistent immunological response to BLV structural proteins, essentially the gp51 envelope glycoprotein and the mayor core protein p24. We describe the test procedure of an indirect ELISA (...